Bp And Corporate Social Responsibility - 1584 Words

Warren Buffet once said â€Å"it takes 20 years to build a reputation and five minutes to ruin it. If you think about that, you’ll do things differently.† BP could have used Buffet’s quote as a recipe for success. British Petroleum best known as BP, a leading billion-dollar oil corporation is just one of the organizations who participates in corporate social responsibility (CSR). According to their code of conduct â€Å"we are committed to avoiding damage to the environment and related impacts on communities.† BP has put themselves on the line when the oil spill of 2010 occurred in the Gulf of Mexico, with consumers questioning their true meaning and intentions of corporate social responsibility and to what extend they participate in it. BP used†¦show more content†¦Another unfortunate incident happened in 2006 when BP ignored safety warnings that resulted in 267,000 gallons of crude oil accumulating in Alaska’s Bay. This was simply a forec ast of what was to come in the future. When the corporation leased the Deepwater Horizon for half-a-million-dollars a day they were forced to speed up operations in order to avoid loosing money and to continue collecting profit. The carelessness in the use of the technology and concentrating strictly on profit instead of responsibly caring for the environment or society caused the oil spill. After suffering backlash from their spill, consumers and market analysis were skeptical of their intensions and corporate social responsibility. Unfortunately, even after the event of 2010 BP was more concerned with how to retain their investors instead of rebuilding their image to keep their customers returning. In reference to a Forbes article stating â€Å"Yet virtually every BP press release or CEO commentary about reputation links rebuilding trust to rebuilding shareholder value.† One might pose that the corporation should be rebuilding their image by being more involved in the envir onment and helping to rebuild the effects of the disastrous event. They should at least be responsible for holding their end of the promise as far as being careful not to cause harm to the environment or society. To no surprise, BP has spent a

Jean Piaget s Theories On Learning - 1056 Words

As a future educator, I believe that every child that I will teach has a unique way of learning and needs a stimulating atmosphere to learn efficiently. Over the years teaching, children grow socially, emotionally, intellectually, and physically. Being an educator, it is my responsibility to help them fulfill each of these areas to their fullest potential. Doing so, I have to provide them a safe environment, opportunities to share new ideas, and encourage to take risks. The children that I will be teaching in special education will range from ages four to thirteen years old. By taking educational psychology this semester, it has helped me learn that there are many theorists who provide their theories on learning. Certain theorists stuck out to me in which they hypothesized how educating should be brought upon or the stages that one needs to fulfill before moving on. Piaget, Vygotsky, and Maslow all address theoretical perspectives, which I believe will play a role in my teaching phil osophy. Jean Piaget hypothesized that children go through a series of four stages: sensorimotor, pre-operational, concrete operational, and formal operational stage. In teaching, I will focus on the pre-operational, concrete operational, and formal operational stages because of the age range that I will be teaching in special education. Each stage focuses on a different aspect of development and accomplishments that go with it. The pre-operational stage, age’s two to seven, states that childrenShow MoreRelatedThe Importance Of Sensory Experience For Learning : Jean Piaget s Theory Of Intellectual Development882 Words   |  4 Pagesthis was a firsthand learning experience taught to me by my senses, this scenario perfectly describes the way children learn the senses enhance play, they are natures ultimate teacher. In the document â€Å"The Importance of Sensory Experience for Learning: Jean Piaget’s Theory of Intellectual Development† It gives the reader a quic k understanding of Piaget’s understanding of children and their important use of senses. It is described as the foundation of learning and this learning style guides infantsRead MoreVygotsky And Vygotsky : Early Childhood Development1683 Words   |  7 Pages Amanda Rezzonico Piaget vs Vygotsky Early Childhood Development Lev Vygotsky and Jean Piaget are known in the educational world. Vygotsky and Piaget were developmental psychologists who had many of the same views and beliefs, but at the same time had opposing views. According to Jean Piaget â€Å"cognitive development was a repetitive reorganization of mental processes that derived from biological maturation in addition to environmental experiences’’ (McLeod, S. A. (2015). The childRead MoreJean Piaget s Theory And Theory1673 Words   |  7 PagesWhat is a theory? A theory is an organized set of ideas that is designed to explain development. These are essential for developing predictions about behaviors and predictions result in research that helps to support or clarify the theory. The theorist I am choosing to talk about is Jean Piaget who discovered the cognitive development theory and who broke it down into different stages. The different stages are the sensorimotor stage, the preoperational stage, the concrete operatio nal thoughtRead MoreVygotsky And Vygotsky Theories Of Learning1257 Words   |  6 PagesTheories of learning In this essay, I will compare and contrast jean Piaget and lev Vygotsky theories of learning. First, I will discuss Piaget followed by Vygotsky then I will compare and contrast both theorists. Jean Piaget was a Swiss developmental psychologist and philosopher, he is known for his contribution to a theory of cognitive development. Piaget became interested in the reasons why children gave the wrong answers to questions that required logical thinking. He believed that these incorrectRead MorePiaget s Theory On Stages Of Developmental Psychology1039 Words   |  5 Pages101 9 December, 2015 Piaget Today â€Å"Child development does not mean developing your child into the person you think they should be, but helping them develop into the best person they are meant to be.† ― Toni Sorenson Jean Piaget was a leader in the field of developmental psychology, the study of how people grow. Instead of continuing the Freud s work with psychoanalysis, as many psychologists and philosophers did at the time, Piaget stayed â€Å"closer to his teacher Pierre Janet s psychology† (Vidal)Read MoreEducational Methods Influenced By Jean Piaget And Lev Vygotsky800 Words   |  4 Pagesresearch of Jean Piaget and Lev Vygotsky. Both of these men provided influential theories, which had a significant impact on evaluating children’s learning styles and abilities. After years of research and observation, Piaget determined that intellectual development is the result of the interaction of individual and environmental factors. He felt that as a child develops and always interacts with the world around him, knowledge was established. Through his observations of his children, Piaget developedRead MorePiaget s Theory On Stages Of Developmental Psychology1180 Words   |  5 Pages Piaget Today Rebecca Biddle English 101 Mrs. Rufino 17 December 2015 Rebecca Biddle Mrs. Rufino English 101 9 December, 2015 Piaget Today â€Å"Child development does not mean developing your child into the person you think they should be, but helping them develop into the best person they are meant to be.† ― Toni Sorenson Jean Piaget was a leader in the field of developmental psychology, the study of how people grow. Instead of continuing the Freud s work with psychoanalysis, as manyRead Morejean piaget1284 Words   |  6 Pagesï » ¿Jean Piaget Jean Piaget (1896 - 1980) was employed at the Binet Institute in the 1920s, where his job was to develop French versions of questions on English intelligence tests. He became intrigued with the reasons children gave for their wrong answers on the questions that required logical thinking. He believed that these incorrect answers revealed important differences between the thinking of adults and children. Piaget (1936) was the first psychologist to make a systematic study of cognitiveRead MoreJean Piaget s Theories Of Cognitive Development1360 Words   |  6 Pages Jean Piaget was a Swiss psychologist. He worked in the fields of Developmental Psychology and Epistemology. He’s known for his works and theories in the field of child development. His theories of cognitive development and epistemological views are called, â€Å"genetic epistemology†. Piaget placed the education of children as most important. His works and theories still play a huge role and influence the study of child psychology today. Jean Piaget was born on August 9, 1896 in Neuchatel, SwitzerlandRead MoreJean Piaget: Biography and Theory of Cognitive Development1601 Words   |  6 PagesPiagets Theory of Cognitive Development: Jean Piagets theory of cognitive development is a description of the four distinct stages of development of cognition in children. The theory was developed at a time when Piaget was employed at the Binet Institute in the 1920s in which his main responsibilities were to develop the French versions of questions on the English intelligence tests. During this period, Piaget became increasingly concerned or interested with the reasons children gave for their

Motivation And Hate Groups Free Essays

I think there should be a very good reason as to what motivates people to Join such organizations. I don’t believe in hating something or someone that much to want to destroy it. Personally, in my opinion, people in hate groups, such as the ASK, are racist beings with no life whatsoever. We will write a custom essay sample on Motivation And Hate Groups or any similar topic only for you Order Now These people seem so ignorant they might not even have a very good reason to have Joined a hate group. The ASK lost very many of its members after people started realizing how stupid and ignorant the organization was. I can’t think of much that could motivate people these days to be a part of a hate group. After African Americans gained their freedom, some people were outraged and shocked and with such a big change, I think they were motivated to Join the hate group. But now in 2014, there’s nothing that these people, whatever ethnicity, race, or religion they are, did to the members of the hate group, so there’s no reason to propose violence onto Portia 2 them. Everybody Is different, whether they’re different because of their race, religion, ethnicity, or sexual orientation. For example, not everybody Is fond of gays. Not long ago, Arizona Legislature has passed a controversial bill that would give business owners permission to deny service to gay and lesbian costumers. In my opinion, the bill is ridiculous, but It Just goes to show how people who actually take advantage of the bill are dumb-minded. How could people be so Ignorant? I mean, what did these people ever do to you? I don’t think I will ever hate anything so much as to Join a hate group. Sure, there are some things I don’t like, Like people being mean or bullying ACH other, but I don’t think I’d ever stoop to such a low level to Join a hate group, Like the ASK. I would never hurt or put someone In danger because I didn’t Like his or her race or religion. In my pollen It’s hostile to propose violence to stop something you hate or dislike. People hate things so much that sometimes they commit to use violence to try to stop It and get rid of It. They Join groups that promote and practice hatred and violence towards members of a different race, religion, ethnicity, sexual orientation and any other things that make people differ from each other. One of these hate groups Is the UK Klux Klan, or also known as the ASK. People Join these groups out of racism and Ignorance, because there Is no rational explanation as to why they do so. Motivation And Hate Groups By weakling Everybody is different, whether they’re different because of their race, religion, ethnicity, or sexual orientation. For example, not everybody is fond of gays. Not long bill is ridiculous, but it Just goes to show how people who actually take advantage of the bill are dumb-minded. How could people be so ignorant? I mean, what did these group. Sure, there are some things I don’t like, like people being mean or bullying each other, but I don’t think I’d ever stoop to such a low level to Join a hate group, like the ASK. I would never hurt or put someone in danger because I didn’t like his or her race or religion. In my opinion it’s hostile to propose violence to stop something you stop it and get rid of it. They Join groups that promote and practice hatred and groups is the UK Klux Klan, or also known as the ASK. People Join these groups out of racism and ignorance, because there is no rational explanation as to why they do so. How to cite Motivation And Hate Groups, Papers

Schizophrenia And Schizoaffective Disorder â€Myassignmenthelp.Com

Question: Discuss About The Schizophrenia And Schizoaffective Disorder? Answer: Introducation In mental health nursing, recovery does not refer to the complete recovery from the mental health issue in a way one recover from physical problem. In some cases, it is defined as staying in control despite of experiencing mental health issue. This led to the development of recovery principles where it focused on building resilience and support recovery of mentally ill people and not just treatment or management of symptoms. There is no single way to define recovery of mental ill patients, however, to guide them so that they lead a meaningful life. The lived experience of 50 year-old Jeremy Oxley is a prime example of recovery where he survived thirty years living with schizophrenia. He was a guitarist in the band named Sunnyboys and was front man in the highly successful pop-rock band. The strength and courage he mustered and his return to the stage is itself a heroic performance. Therefore, the following discussion involves the exploration of mental health problems experienced by J eremy and incorporation of National Recovery Framework and principles. The video shows the live of Jeremy Oxley who was a famous guitarist in the popular Australian band, Sunnyboys. The documentary video shows the remarkable journey where he had survived 20 years living with schizophrenia. In the early 1980s, Oxley at the age of 18 years touted as the most talented songwriter or singer in Australia and was the front man in the highly successful band. He performed along with his older brother, Peter who was the bass guitarist. They achieved rapid success during those years and like a typical musical industry, he became trapped in the relentless touring and hectic recording sessions. This created extreme stress due to excessive work and he was unable to bear the mental and physical burnout. His health was crushing down and on April 2012, Jeremy walked out of the Enmore Theatre without any reason. Little he knew or his brother what was lurking, gradually stress triggered a downward spiral and trapped Jeremy into lonely horror of schizophrenia (The Sunnyboy , 2013). Jeremy is a very funny and gentle person. He was a perfectionist as described by his childhood friend, Bill Bilson who was a drummer in the band and prior to guitar playing, he was in surfing. Suddenly, when he started having disturbed and paranoid thoughts and highly stressed due to his hectic schedule. He was getting arrogant during the shows and became a drunkard. He sought the refuge of alcohol and drugs. The newspapers started describing him as down and out and he could not continue with his band performance. That was the moment when schizophrenia was taking a heavy toll on his life and health. Hi brother, Peter was at loss to understand the bizarre behaviour of his brother that ultimately led to the demise of the famous band, The Sunnyboys. In this condition, Jeremy was unable to understand that he was suffering from mental illness and denied medical treatment and finally, the brothers were apart. He became a complex personality hidden in layers and was unable to figure out what was happening around him. He started experiencing auditory hallucinations and heard voices who were talking about him. He could hear his mother and brothers voice even when they are not around. He started hearing voices saying that everyone stated liking Peter more than Jeremy. He felt as if his music is stolen from him. These are the classic symptoms of schizophrenia in which individuals hear more than one voice that are familiar discussing about his or her behaviour. This is of great diagnostic significance and classified as first-rank symptom for schizophrenia. Jeremy did not believe that he had schizophrenia. He was unable to figure what was wrong with him and so he denied medical treatment. This is the reason he showed non-compliance to treatment and medications. He was suffering from diabetes and unusual heart rhythms; despite of that he did not maintain a healthy regime. According to Chandra et al., (2014) the persons experiencing psychotic episodes are not willing to understand their mental health condition and seek refusal. This affects their recovery process and quality of life. This was also depicted in the lived experience of Jeremy where he denied his medical illness condition as he lacked insight into schizophrenia. He never looked himself and when finally Mary Griffiths, his wife helped him to recover from this mental condition. Recovery in schizophrenia is personal recovery rather than clinical recovery. Personal recovery can be defined in a way the people expertise with lived experiences of mental illness that is different from clinical recovery. It is a way in which a person develops a unique process of changing values, attitudes, skills, goals, feelings and roles (Cavelti, Homan Vauth, 2016). It is way of leading a hopeful, satisfying and contributing life despite of illness limitations. The recovery process involves adding purpose and new meaning to ones life so that they grow beyond the catastrophic effects of the mental illness. Since, schizophrenic is a complicated mental illness condition, the personal attitude and beliefs are important for the recovery process. Patients with schizophrenia require proper guidance and emotional support so that they are able to live well within limits of mental illness (Hasson-Ohayon et al., 2014). For Jeremy, his wife, Mary acted as the guiding factor that supported him throughout his journey of schizophrenia. They lived a happy life with her and two children, Kieran and Lachlan who also provided supported him during the recovery process. According to National Recovery Framework, there are six major principles of recovery in mental health practice that defines recovering in gaining and retaining the hope, engagement in active life, understanding of ones disabilities and abilities, social identity, personal autonomy and providing a positive sense of self. The first principle explains the uniqueness of an individual. It states that recovery is not about cure but providing them opportunities for making choices and living a satisfying, meaningful and purposeful life being considered a valuable member of the community (health.gov.au, 2013). It put emphasis on the quality of life, social exclusion and empowering of individuals. In the similar way, Jeremy was empowered by Mary to make his individual choices while making him a part of her family and two children. Kieran and Lachlan considered Jeremy as their father providing him emotional support and social status and a part of their family. The family recognized Jeremys importance and provided him ample of support and care they he received. Mary empowered him that recognized his uniqueness and gave him place in his family that strengthened his social identity. The second principle is defined as a way in which the individuals with mental illness are supported and empowered to make their own choices in leading their lives and acknowledgement of choices that are creatively and meaningfully explored (health.gov.au, 2013). In the given case scenario, during his recovery period, Jeremy was empowered to make his individual choices so that he led a meaningful life. He was indulged in painting where he put his all emotions, thoughts and philosophy. He conveyed his thoughts and expressed his creativity through his paintings. He taught the children how to play guitar and they were happy as it was depicted in the video. These engaging acts supported Jeremy to build his strengths and take responsibility of his own life. It also ensured balance between support and duty of care for making Jeremy make use of his opportunities. The fourth principle is dignity and respect where recovery is respectful, honest and courteous in all interactions. It also involves respect and sensitivity for each individual in their beliefs and values. In the given case, Mary and her two children respected Jeremy and they were in active conversation with each other. She respected him and gave value to his beliefs and opinions where he felt respected and dignified in the family. The fifth principle is about partnership and communication. In the given case scenario, it is acknowledged that Jeremy was in active conversation with Mary where she supported him in a way that made sense to him. He communicated well with Marys children and she worked well with him. Mary became the most important factors for his recovery where she was involved in a realistic and positive manner with Jeremy to help him realize his own goals, hopes and aspirations. As per the National Recovery Framework, personal recovery principles were well illustrated in the lived experience of Jeremy. Mary supported him by empowering his strengths and beliefs by providing emotional support. She taught that he should not blame others for the choices he made. She was patient during the whole recovery journey and supported him to the fullest and he finally made a comeback to the pop-music industry after 21 years that was commendable and helped him lead a normal life despite of his mental illness. There was proper communication, empowerment and support; although Jeremy mentions that, he is still seeking answers for his illness and believe that life is what one make out of it. From the above discussion, it can be concluded that lived experience of Jeremy Oxley greatly influence the mental health services. It is important to incorporate recovery principles in mental health practice and provision of services. It is evident in the documentary that Jeremy who lived with schizophrenia, his wife, Mary Griffiths has participated enthusiastically and support during his illness. Her optimism and passion is inspirational and truly collaborative in nature. His lived experience shows the incorporation of recovery principles and after 21 years, how he returned to the stage. National Recovery Framework defines and illustrates the lived experience and recovery and describes recovery-based principles for guiding mental health professionals to tailor approaches for the people with mental health issues. Therefore, mental health principles are important for the overall recovery of people living with mental health problems. References A national framework for recovery-oriented mental health services: Guide for practitioners and providers. (2013).health.gov.au. Retrieved 17 September 2017, from https://www.health.gov.au/internet/main/publishing.nsf/content/67d17065514cf8e8ca257c1d00017a90/$file/recovgde.pdf Cavelti, M., Homan, P., Vauth, R. (2016). The impact of thought disorder on therapeutic alliance and personal recovery in schizophrenia and schizoaffective disorder: An exploratory study.Psychiatry research,239, 92-98. Chandra, I. S., Kumar, K. L., Reddy, M. P., Reddy, C. M. P. K. (2014). Attitudes toward medication and reasons for non-compliance in patients with schizophrenia.Indian journal of psychological medicine,36(3), 294. Department of Health | Principles of recovery oriented mental health practice. (2017).Health.gov.au. Retrieved 17 September 2017, from https://www.health.gov.au/internet/publications/publishing.nsf/Content/mental-pubs-i-nongov-toc~mental-pubs-i-nongov-pri Hasson-Ohayon, I., Mashiach-Eizenberg, M., Elhasid, N., Yanos, P. T., Lysaker, P. H., Roe, D. (2014). Between self-clarity and recovery in schizophrenia: reducing the self-stigma and finding meaning.Comprehensive psychiatry,55(3), 675-680. The Sunnyboy. (2013). Retrieved from https://edutv.informit.com.au.ezproxy1.acu.edu.au/watch-screen.php?videoID= 655842

Loss of Biodiversity and Extinctions

Discovery to Debacle Essay Example

Discovery to Debacle Essay Example Discovery to Debacle Essay Discovery to Debacle Essay Introduction: The outgrowth of the monoclonal antibodies as regulative T cell activators raised a great ardor among research workers to develop them as potent go-betweens for immunotherapy. Although many of these monoclonal antibodies have been marketed for the intervention of assorted diseases [ 1 ] ( Bhogal, 2007 ) , some of them were unable to make this finish due to their discontinuance in the clinical phases. One such model theoretical account is TGN1412. TGN1412 is an IgG4 type of monoclonal antibody which acts as superagonist for CD28, a co-stimulatory receptor required for T-cell activation. Since TGN1412 activates the T cell without anterior activation of the T cell antigen ( TCR ) receptor it was designated as a superagonist [ 2 ] ( Bhogal, 2006 ) . However, the vision of using TGN1412 as an anti-inflammatory agent was crashed when it failed in the first measure of the clinical surveies. The stage 1 clinical test of this promising drug emerged to be a catastrophe taking to dangerous effects in the voluntaries. This reappraisal focuses on the find, presymptomatic development and ethical concerns related to the drug and the possible mistakes made during the period from its find to the ruin. All the above factors had a cascading consequence and contributed greatly to the drug s failure. This fiasco of TGN1412 demands the important change in the current drug testing form for the advancement of the hereafter development of drugs. Development: -To promote the activation of immunosuppressive regulative T-cells, TeGenero, a German Pharmaceutical company developed TGN1412, a wholly humanized monoclonal antibody by protein technology of the non-human species generated antibody ( mice antibody ) to obtain belongingss specific to worlds. Protein technology involved the transportation of the complementary determining parts of a mouse anti-human CD28 ( 5.11.A1 ) antibody into human antibody concatenation proteins derived from Chinese hamster ovary ( CHO ) cells [ 1 ] ( Bhogal, 2007 ) . Autoreactive T-cells doing redness and autoimmunity against certain cells and organic structure tissues are kept in changeless cheque by regulative T cells. Normal T cell activation requires both the T cell receptor and CD28, a receptor protein on surface of T cells for its proliferation and activation [ 3 ] ( Vitetta, 2006 ) . Harmonizing to surveies conducted by TeGenero, TGN1412 can trip the T cells of all specificities and release c ytokines by aiming an antigenic determinant of CD28, a extremely conserved part of CD cringle which is exposed on the extracellular surface of T-cell membranes, therefore short-circuiting the demand to T cell receptor specificity. With this hope of stamp downing the immune system by activation of regulative T cells, TGN1412 was developed as a fresh therapy for autoimmune and inflammatory diseases. In Rheumatoid Arthritis, an autoimmune disease, TGN1412 reduced the degrees of inflammatory go-betweens by activation of the T-cells. B-CLL, most common type of chronic leukaemia is associated with a high white blood cell count and slow accretion of a peculiar type of B-cell. TGN1412 is effectual in intervention of B-CLL by non merely triping and exciting the growing of lymph cells but besides heightening the antigen showing ability of B-cells associated with the B-CLL. [ 2 ] ( Bhogal, 2006 ) After complete development, pre-clinical and carnal testing, TeGenero decided to continue with first in human clinical test to measure the safety, tolerability and pharmacokinetics of TGN1412 and supervise its immunogenicity and effects on T cells, B cells and on cytokine degrees in blood serum. For this intent TeGenero recruited Parexel, a separate clinical test unit. The test protocol submitted by Parexel was authorized by Medical wellness regulative bureau ( MHRA ) on 27th January 2006 approved by Medical Ethics commission on 14th February 2006. [ 2 ] ( Bhogal, 2006 ) Phase 1 Clinical test failure: Harmonizing to the test protocol designed, on 13 March 2006, the first group of 6 voluntaries received a dosage of 0.1mg/kg on and was scheduled to have farther escalating doses over three-week period. However, the test turned ruinous and had to be suspended when these voluntaries developed cytokine release syndrome with an unmanageable addition in tissue cytokine concentrations finally taking to multiple organ failure. [ 4 ] ( Schraven, 2008 ) Preclinical: The probe conducted by MHRA and the European governments after the clinical test stated that there were no mistakes in fabrication, preparation and no marks of taint in the batch TGN1412 administered to the voluntaries [ 4 ] ( Schraven,2008 ) . With the purpose of forestalling such fatal events in future, the expert groups were recruited by Secretary of the province for wellness to look into the mistakes taking to failure of the test. The presymptomatic surveies with regard to the species choice, invitro and exvivo testing, appropriate dose choice and carnal surveies were points subjected to re-examination. In-vitro testing: Sing the species choice, non human Primatess are most frequently considered for the presymptomatic testing due to their close familial and pharmacological similarity to worlds. In instance of TGN1412, Rhesus macaques and the cynomolgus monkeys were used as the theoretical account for surveies on the footing that the 6 amino acid epitope on the C D loop of CD28 to which the drug appears to adhere is wholly similar and conserved in both the macaques and the worlds. [ 5 ] ( Stebbings, 2009 ) After careful designing of the TGN1412 based on the conserved sequence of the non-human Primatess, it could place the recombinant human cells showing CD28 with high adhering affinity. Specificity of TGN1412 for CD28 was confirmed with adhering surveies on the human cells showing CD-28, Cytotoxic T lymphocyte antigen-4 ( CTLA-4 ) and the inducible co-stimulator ( ICOS ) , in which TGN1412 did non expose cross-reactivity with the CTLA-4 and ICOS with the fact that both these proteins have high grade of amino-acid sequence homology with CD28. In order to further synergize the species selectivity, adhering ability of TGN1412 in the human, Macaca mulatta and cynomolgus monkeys and gnawers and marmoset T-cells was evaluated. It was found that nanomolar concentration of TGN1412 could adhere specifically to human and Macaca mulatta and cynomolgus monkeys but non with marmoset and rodent T-Cells due to difference in the antigenic determinant of the marmoset and human CD28. In marmoset species , 2 of the amino acids out of 6 differ as compared to rat in which all 6 amino acids are different, therefore impacting the binding of the TGN1412 to CD28 of these species. All these surveies prompted the research workers to continue with the surveies on the Macaca mulatta and cynomolgus macaques. [ 1 ] [ 2 ] ( Bhogal, 2006, 2007 ) Along with pre-dominant look in human lien, CD28 is besides expressed in the lymphatic, respiratory, connective and female generative tissues. Even though being cognizant of this fact, the cross-reactivity surveies in cynomolgus monkeys were performed with limited tissues non accounting for complete tissue distribution of TGN1412. In add-on to this, cross-reactivity was observed with the respiratory CD28 which was unexplained in the redirect examination of presymptomatic trials since respiratory disfunction was observed in the voluntaries who participated in the test. [ 2 ] ( Bhogal, 2006 ) . Thus it was suggested that executing such surveies with wider assortment of tissues would greatly assist in the hereafter development of immunobiologics. In add-on to binding and the cross responsiveness surveies, invitro trials with human peripheral blood mononuclear cells ( PBMC ) were performed for foretelling the invivo specificity and the species sensitiveness for TGN1412 [ 5 ] ( Stebbings, 2009 ) . Since most maps of the antibodies are mediated by adhering of their Fc part to Fc receptor incorporating cells [ 4 ] ( Schraven,2008 ) , in-vitro trials finding specificity, with Fc immobilized TGN1412, which mimicked the Fc binding were performed in cynomolgus monkeys and adult male, due to high grade of similarity in their sequence homology of the Fc receptor. It displayed that TGN1412 could arouse the response merely when it was immobilized onto a surface, or coupled via immobilized Fc-specific antibody. In contrast to the above consequences, immobilisation of TGN1412 in the cynomolgus monkeys did non demo its action as a superagonist [ 5 ] ( Stebbings, 2009 ) . Alternatively it acts as conventional CD28 agonist necessitating T-cel l receptor and CD28 activation for T cell stimulation and above all that it did non trip the cytokine production as seen in the voluntaries in the clinical tests [ 2 ] ( Bhogal, 2006 ) . All these consequences indicated hapless species choice for the presymptomatic trials. Animal Trials: Pharmacokinetic and toxicological issues have been taken into consideration in correspondence with carnal surveies. Pharmacokinetic appraisals made during the comparative survey of the TGN1412 with its variant TGN1112 in Macaca mulatta macaques, indicated that after their IV disposal, both the drugs were present in the blood serum for 20 yearss, with the peak concentration of the T-cells and no indicant of the increased cytokine degrees. Due to the overestimate of these effects in invitro surveies, 28 twenty-four hours surveies were performed in the cynomolgus monkeys. The half life of TGN1412 in these surveies was found to be 8 yearss with ascertained addition in the expansion of the lymph nodes and enlargement of the CD4+ T-cells. Furthermore, 50mg/kg was set as the no-observed-adverse consequence degree ( NOAEL ) even though these surveies indicated 5mg/kg as an optimum dosage for TGN1412. With respects to the 28 twenty-four hours toxicologic surveies conducted in the cynomolgus monkeys, there was no indicant of the drug related toxicity and half life was similar to the pharmacokinetic trials. All the above consequences supported TeGenero in continuing with the clinical tests in homo for proving the safety and efficaciousness of the drug. [ 2 ] ( Bhogal, 2006 ) Methodological and Ethical concerns: -The calamity of the TGN1412 alerted the field of immunotherapeutics, to non merely meticulously study presymptomatic trials but besides safeguard the ethical regulations associated with each procedure in drug development. Sing the methodological concern, the disposal of appropriate dosage is really important. The dosage of 50mg/kg of TGN1412 for the disposal into the voluntaries was selected on footing of no-observed-adverse consequence degree ( NOAEL ) which was a high dosage [ 5 ] ( Stebbings, 2009 ) . However, the dosage selected should be of optimum concentration, optimum signifies that it should be low plenty to protect the safety of the voluntaries and high plenty to arouse the response for which it is tested. Thus the choice of the dosage should be based on use of all relevant information known about the drug including the freshness, species specificity and mark distribution, in vivo dose response curve and receptor tenancy with regard to concentration. From the invivo dose response curve obtained from the surveies on the Human PBMC, bell shaped dose response curve was obtained with optimal responses between 2-10ug/ml. These consequences stated that the dosage should be selected from the scope of doses falling within this curve and implied the usage of MABEL ( minimal anticipated biological consequence degree ) attack for choosing the safe and optimum dosage for the tests [ 5 ] ( Stebbings, 2009 ) . Second, the design of TGN1412 test required the disposal of the drug to six voluntaries within short clip continuance of two proceedingss. Since monoclonal antibodies have fresh mechanism of action, disposal into fewer voluntaries with sufficient clip intervals is recommended. A better method would be detecting the consequence of such drug in one voluntary before continuing with the test. A good pattern of documenting the medical history of voluntary was non followed in the instance of TGN1412 by the test carry oning grou p, Parexel. [ 6 ] ( Ferguson, 2009 ) Sing the ethical issues, each test performed must be in concurrency with the Helsinki s declarations to safeguard the rights and safety of each take parting voluntary. Conversely all take parting groups including the voluntaries and the research groups must follow the ethical guidelines. The inside informations of the approved survey by the Ethics commission must be given to the voluntaries. Consent signifier must be short, concise and comprehensive and each voluntary should be given adequate clip to analyze and do determination sing take parting in the test. In instance of any inauspicious events, the test groups must describe it instantly to the moralss commission to avoid put on the lining the life of participants. In instance of TGN1412 each voluntary was given a big amount of money as compared to other stage 1 tests. In add-on, the clip given to analyze the long consent signifier was limited [ 6 ] ( Ferguson, 2009 ) . Therefore, attention should be taken that none of the regulat ions are breached under any fortunes. The chief aim of the investigational survey on failure of TGN1412 was to better the drug development procedure and cut down its clinical failure. However, even after this catastrophe in 2006, many of the late developed drugs have undergone failure. Taranabant ( MK-0364 ) was developed by Merck A ; Co. for intervention of fleshiness, which is frequently associated with increased hazard of developing cardiovascular diseases, diabetes and malignant neoplastic disease [ 8 ] . Taranabant is a fresh reverse agonist of cannabinoid-1 receptors ( CB1R ) , which are of import in ordinance of organic structure weight, energy usage and lipid and glucose metamorphosis [ 9 ] ( Pacher, 2009 ) . The thought of cannabinoid exciting appetency was based on utmost hungriness experienced by hemp tobacco users [ 8 ] . This observation led to the birth of Taranabant which stimulates weight loss by adhering to cannabinoid receptors and forestalling their activation. The presymptomatic surveies indicated th at acute disposal of Taranabant inhibited the food-intake and weight addition in dose dependent form, therefore taking to weight loss and lessening in organic structure fats which were non observed in smasher mice deficient in the CB1R cistron. Based on these surveies it was found that merely 30-40 % CB1 receptor tenancy was required to advance weight loss. These consequences from presymptomatic surveies inspired the research workers to continue with clinical tests. The first clinical survey was carried out in 24 healthy voluntaries as random, double-blind and placebo controlled test. This survey was successful as it displayed additive and dose dependent addition in AUC0 and Cmax values, long half life of 38 to 69 hours and mild inauspicious events [ 10 ] ( Addy, 2008 ) . Phase II test carried out for 12 hebdomads in 533 patients confirmed that effectivity of Taranabant in bring oning weight loss as compared to the placebo. Phase III test was initiated in 2400 patients and was inten ded to be continued for 2 old ages. Even after 1 twelvemonth of stage III survey in March 2008, Taranabant was found effectual in cut downing dual sum of weight by dosage of 2mg of drug with combination of exercising and diet. However, in October 2008 it was withdrawn due to GI and CNS side effects associated with it. [ 8 ] ( www.drugdevelopment-technology.com ) . Gastrointestinal side effects associated were chiefly sickness, purging concern, drowsiness abdominal uncomfortableness, and increased intestine motion. Other drug associated symptoms observed were mood alteration, fatigue and increased sudating [ 9 ] ( Addy, 2008 ) . Happening of all these inauspicious events compels the research workers to retreat a specific drug from the clinical test. Many other drugs which appeared to be innovators in development of assorted diseases have faced the failure during their clinical testing continuance either due to their toxic effects in worlds or due to unsatisfactory degree of consequence for intervention of the disease. Flurizan ( tarenflurbil ) , developed by Myriad Pharmaceuticals was intended for the intervention of Alzheimer s disease by selective take downing the Amyloid degrees. However, it was withdrawn from Phase III clinical test since it was found to be unproductive in bettering the cognitive signals and everyday activities in Alzheimer s disease patients. [ 11 ] ( www.drugdevelopment-technology.com ) Decision: Since monoclonal antibodies have evolved to be one of the promising drugs in intervention of countless diseases owing to their novel mechanism, a argus-eyed reappraisal of the presymptomatic surveies before their disposal into worlds is critical. The presymptomatic surveies of the antibody based drugs should be performed in Primatess possessing wholly matched antigenic site with that in worlds. Apart from the detailed the analysis of the presymptomatic consequences and appropriate species choice, it is important to guarantee that these methods are validated. Standardization of these methods will assist in more accurate extrapolation of the similar effects in worlds and prevent such tragic events in future. Besides elaborate analysis of the comparative measurings of the binding affinities should be done for both human antigen and archpriest antigen, to command the unforeseen structural fluctuations of the proteins. If all these stairss were followed in instance of TGN1412, the awful event might hold been predicted and life of the voluntaries would non hold been on the hazard. A valuable lesson was learnt in the field of research that even a little faux pas in any portion of drug development might take to a large blooper and therefore careful hazard analysis and examination of each measure in the drug development in hereafter will greatly heighten the field of drug find, development and cut down the failure of possible drugs. Mentions: [ 1 ] N.Bhogal and R. Combes, Toxicology in Vitro Vol 21:1227-1232, 2007 [ 2 ] N.Bhogal et.al, ATLA 34,225-239, 2006 [ 3 ] E. Vitetta et.al, Perspective Immunology, Vol 313: 308-309, July 2006 [ 4 ] B. Schraven et.al, Immunity Vol 28:591-595, May 2008 [ 5 ] R. Stebbings et. Al, Current Opinion in Biotechnology, Vol 20: 673-677, 2009 [ 6 ] P.R. Ferguson, The SciTech Lawyer, Vol 5 ( 4 ) , 2009 [ 7 ] MJH Kenter and A F Cohen, Lancet, Vol 368:1387-1391, October 2006 [ 8 ] hypertext transfer protocol: //www.drugdevelopment-technology.com/projects/taranabant/ [ 9 ] Pacher et. al. , Arteriosclerosis, Thrombosis A ; Vascular Biology, Vol 29 ( 1 ) :7-9, Jan 2009 [ 10 ] C. Addy, Journal of Clinical Pharmacology, Vol 48: 418-427, 2008 [ 11 ] hypertext transfer protocol: //www.drugdevelopment-technology.com/projects/flurizan/

African American Children and Religion Research Proposal

African American Children and Religion - Research Proposal Example Others have limited their coverage of the research population, excluding young African-Americans for a variety of reasons. This researcher, however, believes that there is an urgent need for research that highlights the positive aspects of the social behavior of today’s generation of young African-Americans, using data involving a youth research population. It is hoped that such an investigation of an important and growing sector of contemporary American society would contribute to knowledge of African-American culture, more specifically on the aspect of psychology of religion. It is further hoped that the results would provide concrete strategies for action that would inspire present and future generations of African-American families and youth to perform their important role in strengthening a nation founded on and inspired by Christian ideals. Aims of the Study The aims of this study are as follows: 1. To determine the impact of religious practice or non-practice on the social attitudes and behavior of African-American children from the ages 8 to 19 residing in a specific community. 2. To examine the religion-based determinants of positive social attitudes and behavior. 3. To identify and describe the positive religious practice role models of the research population under study. Hypothesis The study will test the following hypotheses: 1. African-American children who engage in positive religious practices develop positive social attitudes and exhibit positive social behavior (H.1). 2. African-American children who do not engage in any type of religious practice do not develop positive social attitudes and exhibit negative social behavior (H.2). Review of Literature and Preliminary Discussions One of America's founding fathers, Benjamin Franklin, stated that "religion will be a powerful regulator of our actions, give us peace and tranquility within our minds, and render us benevolent, useful and beneficial to others" (Isaacson, 2003, p. 87-88). Over the last quarter of a millennium, American society has undergone a seismic shift in several aspects, more notably in the role of religion and the belief that its practice has beneficial effects on society. Several studies (Paul, 2005; Inglehart and Baker, 2000; Idler and Kasl, 1992) have attempted to show the correlation between America's social problems and the negative effects of secularization on the practice of religion, and that such a development would have detrimental consequences to the future of democracy. Aral and Holmes (1996) and Hummer et al. (1999) also showed that this phenomenon is evident not only in America but also in other developed democracies such as Europe and Japan. On the contrary, they argue, democratic nations such as those in predominantly Catholic Latin America and in parts of Africa with societies influenced by Christianity (such as Angola, Democratic Republic of Congo, and Ethiopia) where the people are noted for religiosity often exhibit the worst forms of social behavior. In another study, Barro and McCleary (2003) used the term "spiritual capital" in reference to the social benefits that proceed with the practice of religion. They concluded that Americ a's deep social problems in a period of great economic prosperity and the highest expenditures for health care among

The Main Difference between Aristotles Account of Virtue and Socrates Essay

The Main Difference between Aristotles Account of Virtue and Socrates Account of Virtue - Essay Example This is because it identifies happiness as an activity of the soul which goes together with virtue. Aristotle argues that if what individuals do is the source of happiness then, happiness must identify with activity which goes with virtue. Socrates argued that being virtuous was very much related with increasing individual’s happiness. The controversy between the two is that according to Aristotle happiness should always go in accordance with virtue. On the same note, according to Socrates virtue does not necessarily need to be highly related with happiness. Aristotle attempts to criticize Socrates for his emphasis on Socratic definitions. Aristotle does not completely agree with the argument by Socrates that knowledge is important in as far as virtue is concerned. He thinks that even if there is need for knowledge it is easily attainable as suggested by Irwin (158). Aristotle also draws the analogy between acquiring knowledge and acquiring virtue. He argues that both are gain ed through repeating similar actions. Socrates argues that a virtuous soul should also be well ordered. He also argues that power of knowledge of right and the wrong is the advantage of virtue. This is because the knowledge of the two is important to crafts of measurement. ... He also argues that knowledge of the truth is not very important as one can act accidentally or be directed by someone else. Aristotle explains that virtuous actions are objective and are performed by a virtuous agent. Aristotle is in disagreement with Socrates concerning the nature of vice and ethical value as suggested by Segvic and Burnyeat (78). According to Aristotle for an action to be considered virtuous there must be an agreement with the non-rational desires. The agreement should be for reason to express the actions are supposed to be pursued. Contrary to this, according to Socrates there is no need for prior agreement by non-rational desires concerning the setting of the ends. Therefore Socrates considers that the condition necessary for an agent to attain moral knowledge is through disciplining his or her appetites and passions. The also need to be in a harmonious condition. Aristotle fails to agree with Socrates about non-rational desires lead to errors. Socrates is of th e view that strong non-rational desires results to reason making wrong judgment about what is really good. On his account of, virtue Aristotle disagrees with Socrates denying the possibility of incontinence. Socrates argues that only ignorance of what is good and wrong lies behind apparent incontinence. Contrary to this, Aristotle asserts that Socrates argument conflicts appearances he Aristotle’s perception of incontinence seems to be puzzling and their interpretation is therefore controversial. Aristotle seems to argue that incontinent individual makes the right decision. This is because he or she is moved to action by non-rational appetite that conflicts with the decisions he or she has made. The individual acts on the appetite because its strong as opposed

What sources of information do learner use to get a skill outside of Essay

What sources of information do learner use to get a skill outside of the formal education system - Essay Example These sources of information often avail information to the learner although, at times the learner may be unconscious of it. These sources of information include personal learning experience, families, friends, information and communication technology, digital media, internet, community members among other sources. Acquiring a skill for doing a particular job from people experienced in that line is probably the best way of learning. For instance, interacting with people experienced in rock climbing can help one acquire the technique in the most effective way. Safety techniques for using build anchors use belay devices, use karabiners and quick draws for the beginners of rock climbing can best be learnt together with the experienced climbers who are experts. Also several exercises outside classroom can help one develop a particular skill. Thus several years of gymnastics improves one’s ability to practice yoga. Students may try new things and upon failure to achieve their set objectives, they get assistance from family members (Knight 14). Through family members, a student may acquire a unique skill through copying what the other members of the family do for instance, marrying a vegetarian partner or having a vegetarian parent can make one become vegetarian. Friends from work places or r esidential places can also help one acquire a particular skill. Therefore, doing and attempting to do, forms the basis of a student’s natural acquisition of skills (Volpe 149). Primarily, parents are regarded as the primary educators to their children. For instance, living with a deaf parent can help one acquire the skills of using sign languages (Juul 108). Through a strengthened relationship between the learner and the parents, a learner acquire relevant information that help him impact relevant skill outside classrooms. Parents avail this relevant information to the learners through story telling in the form of narratives, spiritual teachings

Environmental Impact On London Restaurant Industry Tourism Essay

Environmental Impact On London Restaurant Industry Tourism Essay This modern city is vast but its history of growth has left distinct villages that lend it human scale. Each neighbourhood and city of London itself is nearly one having its own restaurant, theatre, gallery and many other attractions. (http://www.secret-london.co.uk/Welcome.html ) London is a cosmopolitan city and there are many historic places to visit in London. There are many businesses running in this historic place. But the business of restaurant is one of the biggest and busiest business in the world. There are Five thousand five hundred seventy restaurants in London. This business has changed the peoples daily life style. Now people want to eat out than they were used to in previous years. Now people like to dine out rather than dine at home. Dining style has been changed with the changing the business of restaurant. In this paper I will discuss how economic recession has affected the London restaurant industry and how boldly and strategically their entrepreneurs have managed to come out of this recession. I will also explain the current and future economic impact on London restaurants. Further, I will describe the role of investments how far they have increased in the presence of tremendous risks. I will also analyze the impact of social and cultural t raditions in this paper. Social life of London has entirely changed. I will also include and scrutinise the social status of the London inhabitants. So Increased congestion and population, rapid growth in factories burning various types of fuel, automobiles spreading poisonous gases and thus polluting the whole atmosphere of London. so all factors responsible for spoiling the London environment will be discussed and the ways and means to rectify will be considered. When to eat and when to sleep: The time for breakfast in London restaurants start from 7:30am but this is only at Workmens Cafes and sandwich bars for office workers. The big restaurants serve breakfast only from 9:00am and continue up to 10:30am. Serving of lunch takes place between noon and 2:30pm and the restaurants serve it only during that period. Tea is served as a separate meal between 4:00pm and 5:30pm and supper is served between 7:30pm and 9:30pm. Only some ethnic restaurants especially Indian, serve meals till midnight. The expected tip is between 10 and 20 percent of the food bill, but there is no tipping in the bars. The wise thing is to avoid eating beef in restaurants, or choose only items which have a low risk of contamination. Many restaurants are closed on Sundays. During Christmas period, the whole city shuts down and meals (The Food Time Line History). Current Restaurants in London: London is a capital city of United Kingdom. In recent decades it has established itself a renowned and most successful city in the world. It has overtaken New York as the worlds most important financial centre. It won the competition to host the 2012 Olympic Games which promoted the restaurants. London has proved to be a world leader in combating economic environmental climatic and social issues. It is the first major city in the world in which restaurants and hospitality has progressed tremendously. Change in consumer style has also compelled the restaurants entrepreneur change their business and cut down their crises and improve their designs to attract new customers. For example Peter Ilic, owner of the Little Bay restaurant group will not present a single food bill to diners at his Farringdon Road restaurant during February. Its entirely up to each customer whether they give  £100 or a penny, he says. All Im asking is that they pay me what they think the food and service is worth. Peter has run restaurants in London for more than 26 years and owns four Little Bay eateries the others are in Kilburn, Battersea and Croydon. Other London restaurants have stuck to the more traditional method of cutting prices to lure out cash-strapped diners. Arbutus, a smart bistro in the West End, has won several awards since it opened in May 2006 but still offers a set lunch for  £15.50, while Kensington-based Tom Aikens offers a lunchtime menu costing  £29, despite possessing a Michelin star. London is a multicultural city according to the different ethnic groups many new restaurants have established. For example Chinese restaurants in china town, Arab or Lebanese restaurants in Edgware road and many Indian Sirilankan and Pakistani restaurants in Tooting and South hall London. (http://www.thisislondon.co.uk/standard/article-23633384-pay-what-you-like-restaurants-recipe-to-beat-the-crunch.do) Current Economic impact: Britain makes it out of recession but chancellor warns to struggle. Growth was described as very weak say shadow chancellor George Osborn. 20 Jan 2010 London Standard Evening. After financial crisis 2008 and worst recession restaurants in London along their entrepreneurs are struggling hard to progress and come up to meet the wants of new customers and guests. Despite recent challenges, confidence among restaurant owners is high with 89% saying that they intend to either maintain staffing levels or even increase staffing levels in 2010, with the majority (57%) e These are the latest results from Business Link in Londons Restaurant Barometer. (http://neighbourhood.statistics.gov.uk ) Sustainability of restaurant market: Renewal review of their monetary support: Cut down prices Offer discounts: Employee demands because of chilly financial climate: Future Economic Impact: Current Investment Impact: To know or asses the gains, profits and estimate rate of investment growth in restaurant sector in London I have selected Luke Johnson. Best known name in restaurant investments.In1993 Luke took control of Pizza express with partners and subsequently became chairman. He promoted business from 12 to 250 restaurants and the share price from 40p to over 900p in 1999 and after selling he started new chain of restaurants which he sold in 2005.He started the new concept of Strada restaurant from scratch and took the chain into 30 units and sold it in late 2005 After total proceeds from these two disposals were 90 million pounds. ( http://www.lukejohnson.org/bio.php) Peter Harden of celebrated Harden restaurant Guides stated when commenting on History of London restaurants There are few people who have had more impact than Luke Johnson. In 2010 he was awarded DEAL OF THE YEAR prize at RETAILERS RETAILER award ceremony. AFTER recession it was very hard time for investment in restaurant industry although press releases showed sign of recovery in restaurant sector in London. October 2009 press release London Festival 8to 13 October. However they still felt chill, of recession wanted increased capital restaurants support. Ashley adviser to Business Link has two advices to restaurant industry. Restaurateurs should be watching costs very closely. They should be exercising a great deal of caution in their forecasting over the next six months and doing as much marketing as possible. The poll found that only half of the respondents have a website. Developing a website and enabling people to make bookings online are vital tools to help restaurants succeed.   Events such as Londons Restaurant Festival are also great ways to garner local support for the industry and market a business. Although there are many hurdles to cross over to bring resigned restaurant industry in same previous booming state they will have to take certain steps . (Eating and Drinking December 31, 2009,12:17PM ) Social Impact on London restaurant Industry: London is fantastic city to live in. It provides sports social clubs and restaurants for all status and class. Whenever you want to meet your friend or, new, strange people and want to learn a new hobby, wish to meet like minded persons restaurants and social clubs will provide. London is a multicultural city; you will see people of different Religions tolerating each other amicably. Britain is a secular country. People in London are not very religious. Very few go to churches. Smoking is banned in public places, in trains and transports. Drinking is very common above 18. It has some limitations. One can make friends with any sex. You can see couple kissing each other anywhere they like without any fear and enjoying their lives. There are also social meeting places in London like clubs and pubs. Multiculturalism: Big Society Concept embraces London: Upgrade restaurant design: Environmental Impact on London Restaurant Industry: There is a very much high environmental impact on London restaurant industry but on the other hand historically London has had low environmental quality but it has also always been a centre for trade and wealth creation. The environmental quality is affected not only by economic activity but also by geographical and weather conditions in London. London is the most densely populated region of England. Population density is around 14 times the average for all other regions. The Cavendish hotel is the best example of environmental impact on London restaurant industry. The Cavendish hotel was the first hotel in London which has been awarded a Gold Accreditation by Green Tourism for London by London development agency (LDA). The aims of the Green Tourism for London scheme is to improve the environmental performance and green credentials of hotels, venues, guesthouses, and many attraction across the capital. Also the Green Tourism for London was launched in 2007. http://www.caterersearch.com/Articles/2009/02/13/326189/Cavendish-is-first-hotel-in-London-to-win-Gold-environmental.htm Conclusion: Bibliography: Lashley C. Morrison A., In Search of Hospitality, Butterworth Heinemann, 2000 Current News: Evening Standard, Ep Magazine, Eating and Drinking, London Time Out 201l, The Times

Video Games: Assassin Simulations Essay -- Video Games Violence Papers

Video Games: Assassin Simulations Video game violence has been a wildly debated topic since the beginnings of the industry. The topic evolved from the debate on media violence or violence in print media. However, the video game debate brings a new angle. Video games, because of their immersive nature, are said to have more impact on children. The proponents and opponents of video game censorship do not really fall into traditional political boundaries. The proponents of censorship tend to be some parents and doctors. Those opposed to censorship tend to be those who play the video games themselves. There is a center faction, however. The center faction consists of those doctors and psychologists who evaluate media violence on a purely medical level. The proponents of video game censorship use a lot of pathos, ethos, but little logos. They mainly believe that kids are driven to violent acts through what they observe in their environment. They invoke images of the school shootings at Columbine. They rely on their own ethos, being mostly doctors or self-declared â€Å"experts† on the subject. The center is a bit different. They rely totally on logos and ethos. They provide statistics and ask you to trust their studies. They also attack the studies and logic by the proponents as faulty. But, despite this, they do recognize that video games are getting increasingly violent. The opponents of video game censorship are mostly video gamers like myself, whose only voice is on USENET and popular web-based gaming forums. We don’t have any â€Å"experts† to speak for us, except for those who take a general anti-censorship stance. Video games, being an expression of free speech and not dangerous to our children, should not be censored. Michael... ...nents of censorship were adults when they committed the crime. In addition, video games are an art form and are protected as free speech under the first amendment. Works Cited Brody, Michael â€Å"Playing With Death† The Brown University Child and Adolescent Behavior Letter. v16 i11 (Nov. 2000) Information Access Expanded Academic ASAP. Grossman, Dave â€Å"Teaching Kids How to Kill† National Forum v80 i4 (Fall 2000) Information Access Expanded Academic ASAP. Peck, Peggy â€Å"Brain Cells Victims of Video Violence† United Press International (Dec. 3 2002) Information Access Expanded Academic ASAP. Walling, Anne D. â€Å"Do Video Games Lead to Violent Behavior in Children† American Family Physician v65 i7 p1436 Information Access Expanded Academic ASAP. â€Å"Gangs in Cyber Space† Yahoo Internet Life (Aug. 1, 2002) Information Access Expanded Academic ASAP. Video Games: Assassin Simulations Essay -- Video Games Violence Papers Video Games: Assassin Simulations Video game violence has been a wildly debated topic since the beginnings of the industry. The topic evolved from the debate on media violence or violence in print media. However, the video game debate brings a new angle. Video games, because of their immersive nature, are said to have more impact on children. The proponents and opponents of video game censorship do not really fall into traditional political boundaries. The proponents of censorship tend to be some parents and doctors. Those opposed to censorship tend to be those who play the video games themselves. There is a center faction, however. The center faction consists of those doctors and psychologists who evaluate media violence on a purely medical level. The proponents of video game censorship use a lot of pathos, ethos, but little logos. They mainly believe that kids are driven to violent acts through what they observe in their environment. They invoke images of the school shootings at Columbine. They rely on their own ethos, being mostly doctors or self-declared â€Å"experts† on the subject. The center is a bit different. They rely totally on logos and ethos. They provide statistics and ask you to trust their studies. They also attack the studies and logic by the proponents as faulty. But, despite this, they do recognize that video games are getting increasingly violent. The opponents of video game censorship are mostly video gamers like myself, whose only voice is on USENET and popular web-based gaming forums. We don’t have any â€Å"experts† to speak for us, except for those who take a general anti-censorship stance. Video games, being an expression of free speech and not dangerous to our children, should not be censored. Michael... ...nents of censorship were adults when they committed the crime. In addition, video games are an art form and are protected as free speech under the first amendment. Works Cited Brody, Michael â€Å"Playing With Death† The Brown University Child and Adolescent Behavior Letter. v16 i11 (Nov. 2000) Information Access Expanded Academic ASAP. Grossman, Dave â€Å"Teaching Kids How to Kill† National Forum v80 i4 (Fall 2000) Information Access Expanded Academic ASAP. Peck, Peggy â€Å"Brain Cells Victims of Video Violence† United Press International (Dec. 3 2002) Information Access Expanded Academic ASAP. Walling, Anne D. â€Å"Do Video Games Lead to Violent Behavior in Children† American Family Physician v65 i7 p1436 Information Access Expanded Academic ASAP. â€Å"Gangs in Cyber Space† Yahoo Internet Life (Aug. 1, 2002) Information Access Expanded Academic ASAP.